therapy spotlight

Tissue Regeneration

Safe, Noninvasive Help for Arthritis, Joint Disease and More

by Keri Topouzian, D.O.

Tissue Regeneration, Image:

RRegenerative medicine in the form of exosomes and umbilical stem cells may be the way to go for those suffering with pain, stiffness and inflammation associated with arthritis, osteoarthritis, joint disease and more. These treatments are safe and effective and do not offer the side effects or long-term damage or recovery period of NSAIDs and other medications for these conditions. Patients can often go from not living life to the fullest because of pain, sickness or injury to a state of restoration, rejuvenation and regeneration.

Exosomes are excreted from stem cells and have been used in diabetes, chronic pain, autoimmune disorders, and neurological disorders. Exosomes work similarly to stem cells because they contain growth factors and cytokines, which are different types of proteins that overlap each other in their duties in communicating to cells while repairing and regenerating. Together, growth factors and cytokines guide cellular regeneration in both organs and tissues.

Umbilical stem cells come from the tissue or matrix of the umbilical cord and are not embryonic stem cells. By the time you are a teenager, you have 10% of the number of stem cells you had when you were born. And, as you get older that number and robustness continue to decline. It is thought that the vast majority of chronic illnesses and conditions 'stem’ from the lack of stem cells in your body. So, the greater your stem cell population, the more likely you are to maintain a healthy, youthful body.

Exosomes and stem cells can help through four major actions:
1. Control inflammation
2. Modulate the immune system
3. Stimulate regeneration
4. Reduce scarring

In summary, umbilical cord stem cells can regenerate tissue and reduce scarring with no downtime, allowing people to resume the activities they are missing out on in life.

Keri Topouzian (“Dr. T”) is an osteopathic physician, board certified in functional medicine and emergency medicine with 30+ years’ experience. He has offices in Bloomfield Hills, Saginaw and St. Joseph. For more information, call 248-302-0473 or visit his website:

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